Grilled Chicken Pesto Panini

Featured in: Hearty Family Meals

This Chicken Pesto Panini combines tender grilled chicken breasts seasoned with salt and pepper, spread with aromatic basil pesto, layered with fresh mozzarella, and finished with optional tomato and greens. The assembled sandwich is pressed until the ciabatta bread turns golden and the cheese melts beautifully. Prepare the chicken in 10 minutes, assemble in 5 minutes, and grill in 4 minutes per side. Serve warm, optionally drizzled with balsamic glaze for added depth.

Updated on Sun, 18 Jan 2026 09:46:00 GMT
Warm grilled chicken, melted mozzarella, and vibrant basil pesto tucked into a golden-brown ciabatta panini, served on a wooden board. Save to Pinterest
Warm grilled chicken, melted mozzarella, and vibrant basil pesto tucked into a golden-brown ciabatta panini, served on a wooden board. | honeyprairie.com

The smell of toasted ciabatta and melting cheese pulled my husband into the kitchen before I even called him for lunch. I was testing a new panini press I'd picked up at a yard sale, skeptical it would actually work better than my cast iron skillet. One bite of that crispy, buttery crust giving way to warm pesto and tender chicken, and we both agreed it was worth every dollar. Now it's our go-to when we want something better than a regular sandwich but don't want to fuss with a full meal.

I made these for a casual Saturday lunch with friends who dropped by unexpectedly. I'd planned to serve something fancier, but all I had were chicken breasts and some pesto I'd frozen weeks earlier. Within twenty minutes, I had four golden paninis on the table, and my friends were asking for the recipe. Sometimes the best meals are the ones you throw together without overthinking.

Ingredients

  • Boneless, skinless chicken breasts: The star protein that becomes juicy and flavorful when seasoned simply and grilled until just cooked through, then sliced thin so every bite has a little chicken.
  • Olive oil: Brushing it on the chicken before grilling keeps the meat moist and helps the seasoning stick without overpowering the delicate flavor.
  • Salt and black pepper: Sometimes the simplest seasoning is all you need, especially when pesto and cheese will add layers of flavor later.
  • Ciabatta rolls: Their airy, chewy texture and sturdy crust hold up beautifully under pressure and absorb just enough butter to turn golden and crispy.
  • Basil pesto: This is where the magic happens, store-bought works perfectly fine, but if you have homemade in the freezer, even better.
  • Fresh mozzarella: It melts into creamy, stretchy goodness that binds everything together and makes each bite feel indulgent.
  • Tomato: Thin slices add a juicy brightness that cuts through the richness, though I'll admit I skip it when my tomatoes aren't ripe.
  • Baby spinach or arugula: A handful of greens adds a peppery freshness and makes the sandwich feel a little more complete.
  • Unsalted butter: Spreading it on the outside of the bread before grilling is the secret to that golden, crispy crust that crackles when you bite into it.

Instructions

Preheat your grill pan:
Get your grill pan or skillet nice and hot over medium-high heat so the chicken gets those beautiful char marks and cooks evenly. If it's not hot enough, the chicken will steam instead of sear.
Season and grill the chicken:
Brush the chicken breasts with olive oil, sprinkle with salt and pepper, then grill them about 5 to 6 minutes per side until the juices run clear and the meat feels firm but not tough. Let them rest for a few minutes before slicing so the juices redistribute and every slice stays moist.
Spread the pesto:
Slather about a tablespoon of basil pesto on the bottom half of each ciabatta roll, making sure to spread it all the way to the edges. This creates a flavorful barrier that keeps the bread from getting soggy.
Layer the fillings:
Arrange the sliced chicken, mozzarella, tomato, and greens on top of the pesto, then cap it with the top half of the roll. Don't overstuff or it will be hard to press and the fillings will slide out.
Butter the outside:
Spread softened butter on the outer sides of each sandwich, which will crisp up beautifully and give the bread that golden color. I use a light hand because too much butter can make things greasy.
Grill the panini:
Place the sandwiches in a panini press or on a grill pan, pressing down with a heavy skillet if you don't have a press, and cook for 3 to 4 minutes per side until the bread is golden and the cheese is melted. The smell alone will make you impatient.
Slice and serve:
Cut each panini in half on the diagonal and serve immediately while the cheese is still gooey and the bread is warm. They're best enjoyed right away, though leftovers can be reheated in a dry skillet.
Freshly pressed Chicken Pesto Panini with juicy sliced chicken, gooey mozzarella, and basil pesto on toasty ciabatta bread. Save to Pinterest
Freshly pressed Chicken Pesto Panini with juicy sliced chicken, gooey mozzarella, and basil pesto on toasty ciabatta bread. | honeyprairie.com

The first time I served these at a small gathering, I watched people take that first crunchy bite and pause, eyes widening just a little. It's that moment when a simple sandwich becomes something worth savoring, something that makes a regular Tuesday feel a little special. Food has a way of doing that when you let it.

Making It Your Own

I've swapped mozzarella for provolone when I wanted a sharper bite, and fontina when I craved something creamier and more nutty. If you're feeling adventurous, try adding a few sun-dried tomatoes or roasted red peppers for extra depth. One time I spread a thin layer of Dijon mustard under the pesto, and it added a subtle tang that surprised everyone in the best way.

Timing and Shortcuts

When I'm short on time, I grab a rotisserie chicken from the store and shred the meat instead of grilling fresh breasts. It cuts the prep down to almost nothing and still delivers all the flavor. You can also prep the chicken a day ahead and keep it in the fridge, then just assemble and grill the paninis when you're ready to eat.

Serving Suggestions

These paninis are hearty enough to stand on their own, but I like serving them with a simple side salad dressed in lemon vinaigrette or a handful of kettle chips for crunch. A glass of crisp Sauvignon Blanc or a cold Italian beer rounds out the meal perfectly, especially on a warm afternoon when you want something satisfying but not too heavy.

  • Drizzle with balsamic glaze just before serving for a sweet, tangy finish.
  • Serve with a light arugula salad tossed in olive oil and lemon to balance the richness.
  • Wrap any leftover panini halves in foil and reheat in the oven at 350°F for about 10 minutes.
A close-up of a Chicken Pesto Panini with melted mozzarella, grilled chicken, and pesto spread on crusty ciabatta bread. Save to Pinterest
A close-up of a Chicken Pesto Panini with melted mozzarella, grilled chicken, and pesto spread on crusty ciabatta bread. | honeyprairie.com

There's something about a well-made panini that feels like a small victory, crispy and warm and put together just right. I hope this one becomes a favorite in your kitchen, too.

Questions & Answers

How do I keep the chicken moist while grilling?

Don't skip the resting period after grilling. Let the chicken rest for 5 minutes before slicing, which allows juices to redistribute throughout the meat, keeping it tender and juicy.

Can I prepare this ahead of time?

Grill the chicken and prepare your pesto in advance. Assemble the paninis just before grilling for the best results, as the bread stays crispier when pressed fresh.

What's the best way to use a panini press?

Preheat your panini press, butter the outside of the sandwich lightly, and press for 3-4 minutes per side. If using a grill pan instead, place the sandwich inside and weigh it down with a heavy skillet.

Are there good substitutes for mozzarella?

Yes. Provolone and fontina are excellent alternatives that offer richer, slightly different flavor profiles while maintaining that creamy, melty quality.

How can I save time preparing this meal?

Use rotisserie chicken instead of grilling fresh breasts, and opt for store-bought pesto. These shortcuts cut preparation time significantly without compromising flavor.

What beverage pairs well with this panini?

A crisp Sauvignon Blanc complements the basil and mozzarella beautifully. For non-wine options, try a light Italian beer or fresh lemonade.

Grilled Chicken Pesto Panini

Juicy grilled chicken meets vibrant basil pesto and creamy mozzarella in this satisfying Italian panini pressed to perfection.

Prep duration
15 minutes
Cook duration
10 minutes
Overall time needed
25 minutes
Recipe by Honey Prairie Abigail Greene


Skill Level Easy

Cuisine type Italian

Makes 4 Number of portions

Diet specifications None specified

What You'll Need

Chicken

01 2 boneless, skinless chicken breasts (14 oz)
02 1 tablespoon olive oil
03 1/2 teaspoon salt
04 1/4 teaspoon black pepper

Panini

01 4 ciabatta rolls, sliced in half
02 4 tablespoons basil pesto
03 7 oz fresh mozzarella, sliced
04 1 medium tomato, thinly sliced
05 1 handful fresh baby spinach or arugula
06 2 tablespoons unsalted butter, softened

How to Make It

Step 01

Prepare grill station: Preheat a grill pan or skillet over medium-high heat.

Step 02

Grill chicken breasts: Brush chicken breasts with olive oil and season with salt and pepper. Grill 5-6 minutes per side until cooked through and juices run clear. Let rest 5 minutes, then slice thinly.

Step 03

Assemble base layer: Spread 1 tablespoon pesto on the cut side of each bottom ciabatta half.

Step 04

Layer sandwich components: Layer sliced chicken, mozzarella, tomato, and spinach or arugula on top of pesto. Cover with top ciabatta halves.

Step 05

Butter sandwich exterior: Lightly butter the outside of each sandwich.

Step 06

Press and grill panini: Heat a panini press or grill pan over medium heat. Place sandwiches in press or pan, pressing down with heavy skillet if needed. Grill 3-4 minutes per side until bread is golden and cheese is melted.

Step 07

Finish and serve: Slice each panini in half and serve warm.

Essential tools

  • Grill pan or panini press
  • Chef's knife and cutting board
  • Spatula
  • Small bowl for pesto preparation

Allergy Details

Go through all ingredients to spot potential allergies. If unsure, check with a health expert.
  • Contains wheat from ciabatta bread
  • Contains milk from mozzarella and butter
  • May contain tree nuts if pesto contains pine nuts
  • May contain eggs in some breads or pestos

Nutrition details (per portion)

Details for informational use only — not a substitute for a medical professional.
  • Energy (calories): 540
  • Lipids: 22 g
  • Carbohydrates: 44 g
  • Proteins: 37 g